Synaptopodin expression in idiopathic nephrotic syndrome of childhood

MicroRNAs in idiopathic childhood nephrotic syndrome.

Childhood nephrotic syndrome (NS) is associated with an increase in the permeability across the glomerular filtration barrier due to processes that affect the dynamics and permselectivity of the glomerular filtration barrier. This increased permeability leads to an inability to restrict the loss of protein to 100 mg/m body surface per day (1 ). The incidence of idiopathic NS has been reported t...

Unanswered questions in childhood idiopathic nephrotic syndrome

Editorial Implication for health policy/practice/research/medical education: Recent advances in molecular genetics have helped in unraveling the genetic component of idiopathic nephrotic syndrome in children. Similar advances in understanding the environmental triggers and immune defects will help better understand the pathogenesis of the disease. It is hoped that the above advancements will ul...

Comparison of Daily versus Every Other Day Treatment Regimen of Levamisole to Control Recurrence in the Childhood Idiopathic Nephrotic Syndrome

Background Idiopathic nephrotic syndrome is a kidney involvement that causes edema and heavy proteinuria with severe complications if the treatment is started late. The present study aimed to assess the efficacy of Levamisole in the daily versus every other day treatment regimen to control recurrence in Childhood Idiopathic Nephrotic Synd...

reversed clinical and morphologic characteristicsof idiopathic childhood nephrotic syndrome

Childhood Idiopathic Steroid Resistant Nephrotic Syndrome, Different Drugs And Outcome.

BACKGROUND The management of steroid resistant nephrotic syndrome (SRNS) is quite difficult in paediatric patients. Not only the remission is difficult but also these patients are at risk of progression to end stage renal disease (ESRD). The goal of treatment is either to achieve complete remission or even partial remission as it is the most important predictor of disease outcome. METHODS Thi...